The planar cell polarity pathway regulates parietal endoderm outgrowth

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The Planar Cell Polarity Pathway and Oriented Migration of Parietal Endoderm Outgrowth

............................................................................2 Introduction........................................................................4 Materials and Methods...........................................................15 Results.............................................................................20 Discussion........................................................

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The zebrafish endoderm begins to develop at gastrulation stages as a monolayer of cells. The behaviour of the endoderm during gastrulation stages is well understood. However, knowledge of the morphogenic movements of the endoderm during somitogenesis stages, as it forms a mesenchymal rod, is lacking. Here we characterise endodermal development during somitogenesis stages, and describe the morph...

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The planar polarity pathway

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The Wnt5/planar cell polarity pathway regulates axonal development of the Drosophila mushroom body neuron.

Axonal development is a fundamental process for circuit formation in the nervous system and is dependent on many cellular events, including axon initiation, elongation, guidance, and branching. The molecular mechanisms underlying these events have been well studied, especially for axon guidance. In the presence of a guidance cue, the polarization of a growth cone precedes the turning response, ...

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Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes.

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ژورنال

عنوان ژورنال: Developmental Biology

سال: 2007

ISSN: 0012-1606

DOI: 10.1016/j.ydbio.2007.03.542